Programming Molecular Association and Viscoelastic Behavior in Protein Networks.

نویسندگان

  • Lawrence J Dooling
  • Maren E Buck
  • Wen-Bin Zhang
  • David A Tirrell
چکیده

A set of recombinant artificial proteins that can be cross-linked, by either covalent bonds or association of helical domains or both, is described. The designed proteins can be used to construct molecular networks in which the mechanism of crosslinking determines the time-dependent responses to mechanical deformation.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

New Model for Visco-Elastic Behavior of Asphalt Mixture with Combined Effect of Stress and Temperature

The analysis of pavements and their ingredients has always been important due to a good understanding of their behavior under different conditions; that leads to more accurate relations. Due to the extent of asphalt mixture application in the world, the assessment of different behaviors of this mix is very important from various aspects of performance and safety. Given that the asphalt mixtures...

متن کامل

Effect of Polymer Grade and Plasticizer Molecular Weights on Viscoelastic Behavior of Coating Solutions

Film coating solutions containing different grades of HPMC (E5, E15 and E50) with and without polyethylene glycol (with various molecular weights) were examined by an oscillatory method, using Haake CV 100 rheometer. Fundamental rheological parameters (?, G? and G² ) were measured over the frequency range from 0.04 to 2 Hz. The variation with frequency of the loss tangent (a ratio of viscous to...

متن کامل

Effect of Polymer Grade and Plasticizer Molecular Weights on Viscoelastic Behavior of Coating Solutions

Film coating solutions containing different grades of HPMC (E5, E15 and E50) with and without polyethylene glycol (with various molecular weights) were examined by an oscillatory method, using Haake CV 100 rheometer. Fundamental rheological parameters (?, G? and G² ) were measured over the frequency range from 0.04 to 2 Hz. The variation with frequency of the loss tangent (a ratio of viscous to...

متن کامل

Calculation of tunnel behavior in viscoelastic rock mass

Wall displacements and ground pressure acting on the lining of a tunnel increase with time. These time-dependent deformations are both due to face advance effect and to the time-dependent behavior of the rock mass.  Viscoelastic materials exhibit both viscous and elastic behaviors. Thorough this study, the effect of different linear viscoelastic models including Maxwell, Kelvin and Kelvin-Voigt...

متن کامل

Study of PKA binding sites in cAMP-signaling pathway using structural protein-protein interaction networks

Backgroud: Protein-protein interaction, plays a key role in signal transduction in signaling pathways. Different approaches are used for prediction of these interactions including experimental and computational approaches. In conventional node-edge protein-protein interaction networks, we can only see which proteins interact but ‘structural networks’ show us how these proteins inter...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Advanced materials

دوره 28 23  شماره 

صفحات  -

تاریخ انتشار 2016